Figure: CAMSAP2-mediated polymerization of microtubules (IMAGE)

Kobe University

Figure: CAMSAP2-mediated polymerization of microtubules

Caption

Top: CAMSAP2-mediated polymerization of reconstituted structures in test tubes as observed via electron microscopy, fluorescence microscopy and total internal reflection fluorescence microscopy, respectively. Below: Model of CAMSAP2-mediated microtubule polymerization/network formation. The following phenomena were observed: tubulin connecting vertically, curling to form ring shapes (tubulin rings), and tubulin protofilaments being integrated side-by-side to form sheets. Key: Green: CAMSAP2, Magenta: Tubulin. LLPS: Liquid-Liquid Phase Separation.

Credit

© 2022, Imasaki, Kikkawa et al. (2022) CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation eLife 11:e77365.

Usage Restrictions

Credit must be given to the creator.

License

CC BY

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.