Protective effects of Ginsenoside Rb1 on aged human GCs. (IMAGE)
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(A) The chemical structure of ginsenoside Rb1. (B) Identification of hGL cells with FSHR. (C) The ROS levels expressed in hGL cells was detected by flow cytometry. (D) Quantitative analysis of the mean ROS fluorescence intensity. (E) Effects of Rb1 on LDH leakage. (F) The levels of MDA as measured by related assay kits. (G) Apoptosis-related protein levels in hGL cells as assessed by western blot. (H) The densitometric analysis of cleaved caspase-3 expression. (I) The densitometric analysis of cleaved caspase-9 expression. Data are expressed as the mean ± SEM from three independent experiments. # P < 0.05, ## P < 0.01 vs. young; *P < 0.05, **P < 0.01 vs. old group. Ginsenoside Rb1 alleviates GCs damage in aged women.
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