Innate Immune Response Against HIV (IMAGE)

Scripps Research Institute

Innate Immune Response Against HIV

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For innate immune system activation against HIV-1, Scripps Research scientists have found that the protein PQBP1’s recognition of incoming HIV-1 particles (depicted in red) is required for cGAS activation, a production of cGAMP (depicted in green), in human dendritic cells. Nuclei (Dapi) are depicted in blue.

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Scripps Research

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