SNMMI 2022 Image of the Year (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

SNMMI 2022 Image of the Year

Caption

Representative case with acute anterior wall myocardial infarction: Myocardial perfusion images using 99mTc-tetrofosmin at rest (first row), 68Ga-FAPI-46 PET (second row), late gadolinium enhancement (LGE) from cardiac magnetic resonance (third row) and schematic drawings of the left ventricle (fourth row). Area of fibroblast activation exceeds infarct area and LGE signal, most common type of myocardial FAP-distribution. Bottom left: Mean areas of perfusion defect, FAPI-signal and LGE of 35 studied patients. Bottom right: Global myocardial FAP volume early after acute myocardial infarction inversely correlates with left ventricular ejection fraction (LV-EF) at follow-up in the chronic stage (n=14 patients).

Credit

Johanna Diekmann, James Thackeray, Thorsten Derlin, Christoph Czerner, Tobias Ross, and Frank Bengel, Department of Nuclear Medicine, Hannover Medical School, Hannover, Niedersachsen, Germany; and Tobias Koenig, Jonas Neuser, Andreas Schaefer, Jochen Tillmans, and Johann Bauersachs, Department of Cardiology and Angiology, Hannover School of Medicine, Hannover, Niedersachsen, Germany.

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