Human NPC before and after using AlphaFold and cryo-ET (IMAGE)

European Molecular Biology Laboratory

Human NPC before and after using AlphaFold and cryo-ET

Caption

Comparison of the models of human nuclear pore complex obtained before (left) and after the use of AlphaFold2 combined with cryo-ET (right). The human nuclear pore complex has the total weight of 120 MDa. The previous models covered only up to 35 MDa. The new model covers 70 MDa.

Credit

Agnieszka Obarska-Kosińska/EMBL and MPI of Biophysics

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License

CC BY-NC-SA

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