Widespread loss of IGF-1 from cortical neurons and an increase in IGF-1 in the reactive astrocytes adjacent to the lesion (IMAGE)

Texas Children's Hospital

Widespread loss of IGF-1 from cortical neurons and an increase in IGF-1 in the reactive astrocytes adjacent to the lesion

Caption

Comparison of the expression of IGF-1 (and other molecules) in brain tissues obtained from infantile spasm patient and control samples. Image courtesy of the authors/Annals of Neurology, 2022.

Credit

Ballester-Rosado CJ et al. A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms. Ann Neurol. 2022 Apr 25. doi: 10.1002/ana.26383. PMID: 35467038.

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