Mapping mutation ‘hotspots’ in cancer reveals new drivers and biomarkers (IMAGE)

University of California - San Diego

Mapping mutation ‘hotspots’ in cancer reveals new drivers and biomarkers

Caption

This artistic rendering illustrates the diversity of mutational processes that generate clustered mutations in human cancer. Depicted here are kyklonas, which are molecular cyclones that cause mutations on circular extrachromosomal DNA (ecDNA), and omikli, which is a molecular fog that causes mutations on linear chromosomal DNA.

Credit

Catherine Eng

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Please credit: Catherine Eng

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