Scheme indicating the roles of FGF21 and NRF2 signaling in sorafenib resistance in HCC (IMAGE)

Science China Press

Scheme indicating the roles of FGF21 and NRF2 signaling in sorafenib resistance in HCC

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Nrf2 and FGF21 positively regulate each other to form a positive feedback pathway and induce sorafenib resistance.

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©Science China Press

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