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Nara Institute of Science and Technology

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Heterozygous loss of the Zbtb38 (Zbtb38+/-) decreased epiblast cell proliferation and increased apoptosis shortly after implantation (E4.5~), leading to early embryonic lethality. Nanog and Sox2 expressions were reduced in the Zbtb38+/- embryos. ICM: inner cell mass.

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Eishou Matsuda

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