Susan Garcia-Recio, PhD (IMAGE) UNC Lineberger Comprehensive Cancer Center Caption “We had two pressing questions we wanted to answer: starting at the genetic level, does the way genes are expressed in a cancer vary in primary tumors compared to its metastases and do these gene expression features vary according to the site of metastasis?” Susana Garcia-Recio said. “We found that around 17% of metastatic tumors had reduced expression of a gene that affects cellular immunity, had specific changes to their DNA and reduced ability of immune cells to infiltrate their environment and fight off cancer cells.” Credit UNC School of Medicine Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.