Activated SAMHD1, an HIV-Fighting Enzyme (IMAGE)

Johns Hopkins Medicine

Activated SAMHD1, an HIV-Fighting Enzyme

Caption

Four identical subunits make up the antiviral SAMHD1 enzyme. Each subunit must bind a molecule of GTP at its A1 site and an A, T, C or G nucleotide at its A2 site before the enzyme can break down additional A, T, C and G nucleotides at its S sites.

Credit

Stivers Lab, Johns Hopkins Medicine

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.