T cells in the pancreas (IMAGE)

La Jolla Institute for Immunology

T cells in the pancreas

Caption

Yellow staining shows CD*+T cells poised to target preproinsulin. The white outline on the right shows the perimeter of an insulin-containing islet in a patient with type 1 diabetes. The image shows that the preproinsulin-specific T cells can wait very close islets, probably poised to destroy the beta cells inside.

Credit

Von Herrath Laboratory, La Jolla Institute for Immunology

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