Diagram of the proposed approach for extracting intact lysosomes. (IMAGE)

Japan Advanced Institute of Science and Technology

Diagram of the proposed approach for extracting intact lysosomes.

Caption

Once magnetic nanoparticles have naturally accumulated in a cell’s lysosomes through the endocytic pathway, the cell membrane is ruptured. and its contents “sifted” for 30 minutes using magnets. At the end of this process, intact lysosomes can be retrieved from the magnets and used to study their structure, metabolites, and protein composition.

Credit

Shinya Maenosono from JAIST.

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