Switching (Mechanism )of Mitotic Pattern That Enables Neurulation (IMAGE)

University of Tsukuba

Switching (Mechanism )of Mitotic Pattern That Enables Neurulation

Caption

Ascidian embryo development shows synchronized mitosis until the 11th cell cycle. This is determined by an asynchronous S-phase counteracted by an asynchronous G2-phase along the anterior-posterior axis, which is controlled by differential cdc25 gene expression. At the 11th cycle, cdc25 expression is reduced, causing loss of G2 regulation, and patterned mitosis that moves as a wave from the anterior to posterior of the embryo. This follows the zipper-like action of neural tube closing.

Credit

University of Tsukuba

Usage Restrictions

This image may be used with appropriate credit and caption.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.