Comparison between Healthy and Mutant Embryo Development (IMAGE)

Babraham Institute

Comparison between Healthy and Mutant Embryo Development

Caption

Mouse embryos part way through development (top) showing a normal embryo and an embryo with a mutation in the Nubpl gene, which affects development and leads to prenatal death. Lower images show cells in the corresponding placentas. The green staining marks the exchange surface where nutrients are transferred between the mother and embryo; note that this layer is missing in the Nubpl mutant placenta. Red staining shows the cells underlying the exchange surface, these are also mostly missing in the mutant placenta.

Credit

Perez-Garcia, Fineberg et al.

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