Where a New Drug Binds to Prevent Leukemia from Proliferating (IMAGE)

Cold Spring Harbor Laboratory

Where a New Drug Binds to Prevent Leukemia from Proliferating

Caption

View at atomic resolution shows how candidate drug BI-7273 fits precisely in BRD9's deep bromodomain binding pocket. In preclinical tests, the drug's binding prevented AML cells from proliferating.

Credit

Vakoc Lab, CSHL

Usage Restrictions

please give credit

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.