Metabolites (IMAGE) Duke University Medical Center Caption Using DNA and RNA markers, ER stress was uncovered as the biological process responsible for the increased risk of heart disease events. Click here for motion graphic. Credit Mark Dubowski for Duke Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.