Amyloid Plaques in Brain Slices (IMAGE)
Caption
Clumps of a damaging Alzheimer's protein (white spots) are scarcer in the brains of mice treated with a DNA-based compound (top) as compared with those given a placebo (bottom). The compound targets APOE4, a genetic variant that magnifies a person's risk of the disease. The findings suggest that targeting APOE could potentially prevent or delay onset of Alzheimer's.
Credit
Tien-Phat Huynh
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