Macrophages Interfere with Immune Checkpoint Blocking Drug (IMAGE)

Massachusetts General Hospital

Macrophages Interfere with Immune Checkpoint Blocking Drug

Caption

A macrophage (red) removing PD-1-blocking antibodies (yellow) from the surfaces of neighboring CD8 T cells (blue), cutting short the drug's activity.

Credit

Sean Arlauckas, PhD, Christopher Garris, Mikael Pittet, PhD, and Ralph Weissleder, MD, PhD, Center for Systems Biology, Massachusetts General Hospital

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