Chromatin Loop Mechanism (IMAGE) Rice University Caption The protein complex that forms DNA loops takes up slack by feeding DNA through from either direction until it hits the DNA keyword, or motif, which acts like a brake. The motifs must point in the correct direction; if they point away from the protein complex, it will not recognize them and will keep taking up slack. Credit A. Sanborn, S. Rao Usage Restrictions Must credit: "A. Sanborn, S. Rao" License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.