BphP1 (IMAGE)

Washington University in St. Louis

BphP1

Caption

Deep-tissue in vivo photoacoustic genetic imaging of reversibly switchable bacterial phytochrome BphP1. The reversible switching of BphP1 enables differential photoacoustic imaging, which dramatically enhances the detection sensitivity of a BphP1-expressing tumor (shown in color scale) in the mouse brain. The overwhelming background signals from non-switchable blood vessels are shown in gray scale.

Credit

Junjie Yao and Lihong Wang

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