Investigating HIV's Pathway to Humans (IMAGE)

Kyoto University

Investigating HIV's Pathway to Humans

Caption

Utilizing the humanized mouse model the team found that HIV-1 Vpu inhibiting tetherin at the beginning of infection (right) is key for successful viral infection. SIVcpz Vpu does not have this function (left) adapting and evolving in order to jump to humans.

Credit

Kyoto University / Sato Lab

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