ESC/E(Z) Gene Network (IMAGE) NIH/National Institute of Mental Health Caption Expression of the ESC/E(Z) gene network was found to be systematically disturbed in PMDD. Credit Peter Schmidt, M.D., NIMH., David Goldman, M.D., NIAAA Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.