Photothermal Effect on Gold Nanorods Enhances Transdermal Drug Delivery (IMAGE)

Kumamoto University

Photothermal Effect on Gold Nanorods Enhances Transdermal Drug Delivery

Caption

Near-infrared light produces a photothermal effect on gold nanorods in a hydrogel skin patch. This heats the skin thereby increasing the permeability of the outermost layer, the stratum corneum (SC), which allows significant transdermal delivery of fluorescently labeled ovalbumin. The goal of this research is the effective delivery of protein-based drugs through the skin. (Image reprinted from the European Journal of Pharmaceutics and Biopharmaceutic, 119, Haine, A. T.; Koga, Y.; Hashimoto, Y.; Higashi, T.; Motoyama, K.; Arima, H. & Niidome, T., Enhancement of transdermal protein delivery by photothermal effect of gold nanorods coated on polysaccharide-based hydrogel, 91-95, (2017), with permission from Elsevier.)

Credit

Professor Takuro Niidome

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