Excitotoxic Lesions (IMAGE)
Caption
Figure 1. Excitotoxic lesions of lateral OFC (lOFC) area 11/13 (A) and medial OFC (mOFC) area 14 (B). The left column in each panel shows the extent of the intended lesion area (lOFC in blue; mOFC in red) on standard coronal sections through the frontal lobe of a macaque brain 36-28 mm rostral to the interaural plane. The middle and right columns in each panel show coronal images at corresponding levels taken from T2-weighted MRI scans obtained within 1 week of surgery from cases 1 and 4 from the lOFC group and cases 2 and 4 from the mOFC group. White hypersignal is associated with edema that follows injections of the excitotoxin ibotenic acid and typically corresponds to the extent of the lesion.
Credit
Pujara <em>et al., JNeurosci</em> (2019)
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