Stuck Dividing (IMAGE)
Caption
In some cancers, including chondroblastoma and a rare form of childhood sarcoma, a mutation in histone H3 reduces global levels of methylation (dark areas) in tumor cells but not in normal cells (arrowhead). Rockefeller scientists found that the mutation arrests the cells in a proliferative state to promote tumor development.
Credit
Laboratory of Chromatin Biology and Epigenetics at The Rockefeller University
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Image may be used only to illustrate the research described in the accompanying release.
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