Search and Replace Genome Editing (IMAGE) Broad Institute of MIT and Harvard Caption 'Prime editing' combines two key proteins and a new RNA to make targeted insertions, deletions, and all possible single-letter changes in the DNA of human cells Credit Susanna Hamilton, Broad Institute Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.