Illustration (IMAGE) UT Southwestern Medical Center Caption Sulfatides bind to the mouse cell surface TLR4?MD-2 receptors to activate downstream signaling pathways that result in inflammation. The middle figure shows a cutaway view of MD-2 to reveal the sulfatide molecules (yellow) within. Credit UT Southwestern Medical Center Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.