Dystrophin Lights Up (IMAGE)

Duke University

Dystrophin Lights Up

Caption

These images highlight the stark contrast between mouse models of untreated Duchenne muscular dystrophy (left) and those treated with a CRISPR-based genetic therapy after one year (right). On the right, green indicates a higher level of dystrophin gene expression. The dark spots in the inset show T cells from these mice responding to the bacterial Cas9 protein, indicating the presence of an immune response to the therapy.

Credit

Charles Gersbach, Duke University

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