Protein Visualization (IMAGE)

Cold Spring Harbor Laboratory

Protein Visualization

Caption

The algorithm called "minimum epistasis interpolation" results in a visualization of how a protein could evolve to either become highly effective or not effective at all. They compared the functionality of thousands of versions of the protein, finding patterns in how mutations cause the protein to evolve from one functional form to another.

Credit

McCandlish lab/CSHL, 2020

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