Icebreaker (IMAGE)

University of Pennsylvania School of Medicine

Icebreaker

Caption

TCF-1 is like an icebreaker ship that initially opens the ice (condensed, closed chromatin) and keeps a path available for other ships (other transcription factors that work in later stages of development) to steam through the now-open water (unwound chromatin).

Credit

Stacie Leigh Bumgarner

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