Kidney Structured Damaged in Diabetes (IMAGE)
Caption
The larger, centrally located structure shown here is a glomerulus in a mouse kidney, which is known to be damaged by diabetes, as made evident by the scar tissue dyed purple in the image. The study authors show that administration of RAGE229 to diabetic mice reduced damage to the glomeruli and surrounding structures in the kidney.
Credit
Reprinted with permission from A. Schmidt et al., Sci. Transl. Med. 13, eabf7084 (2021).
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