Drug compound makes pancreatic cancer cells more vulnerable to chemo (IMAGE)

WashU Medicine

Drug compound makes pancreatic cancer cells more vulnerable to chemo

Caption

Researchers at Washington University School of Medicine in St. Louis have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy. While chemotherapy alone (left panel) can cause some degree of pancreatic cancer cell death, the addition of the compound ATI-450 enhances the effect of chemotherapy (right panel), leading to extensive cell death and disruption of the tumor architecture. Pancreatic cancer cells are shown in green. Dying cells are shown in red. White arrows also highlight dying cells.

Credit

PATRICK GRIERSON, LIN LI

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