Rhomboid Protease Cuts Unstable Target Protein (IMAGE)

Johns Hopkins Medicine

Rhomboid Protease Cuts Unstable Target Protein

Caption

The membrane encourages a coil to form in a target protein (left, pink and yellow) and helps keep the gate (pale blue) of the rhomboid protease (deep blue) from swinging open too far (center). When the target protein enters the watery interior of the rhomboid protease, the upper section of its coil (yellow) falls apart and gets cut (right).

Credit

<i>eLife</i> Journal, Creative Commons License, courtesy of Sin Urban

Usage Restrictions

Creative Commons License, credit <i>eLife</i> journal

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.