Drugs Targeting STING Prevent Inflammation (IMAGE) Walter and Eliza Hall Institute Caption Almost all patients with MND have evidence of TDP-43 (red) being in the wrong place inside motor neuron cells. Mitochondria (blue) provide power to motor neurons, but if invaded by TDP-43, they leak out their DNA (green) which triggers a virus sensor called STING. Drugs targeting STING prevent inflammation and keep MND patient motor neurons alive longer in laboratory tests. Credit Image courtesy of the Walter and Eliza Hall Institute of Medical Research Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.