Whitehead Scientists Bring New Efficiency to Stem Cell Reprogramming (IMAGE)

Whitehead Institute for Biomedical Research

Whitehead Scientists Bring New Efficiency to Stem Cell Reprogramming

Caption

In this image of mouse embryonic fibroblasts undergoing reprogramming, each colored dot represents messenger RNA associated with a specific gene that is active in cells being reprogrammed. Red dots represent mRNA for the gene Sall4, green is Sox2, and blue is Fbxo15. The researchers determined that Sox2 activates Sall4 and then activates the downstream gene Fbxo15, creating a gene hierarchy in the later phase of reprogramming.

Credit

Dina Faddah/Whitehead Institute

Usage Restrictions

Credit required

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.