Cluster Analysis of Copy Number Profiles for CTCs and WBCs from 3 Patients (IMAGE)

Menarini Silicon Biosystems

Cluster Analysis of Copy Number Profiles for CTCs and WBCs from 3 Patients

Caption

a) single cells (CTCs and WBCs) from a patient affected by prostate cancer; cluster A represents 6 CTCs with small or no differences in copy number profiles; cluster B is formed by WBCs clustering, as expected, on a distinct branch of the tree. b,c) single cells (CTCs and WBCs) from 2 patients affected by lung adenocarcinoma. Values are expressed as fold changes respect to the main ploidy.

Credit

Fig. 8 Ferrarini A, Forcato C, Buson G, Tononi P, del Monaco V, Terracciano M, et al. (2018) A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products. PLoS ONE 13(3): e0193689. https://doi.org/10.1371/journal.pone.0193689

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Copyright: © 2018 Ferrarini et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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