Figure 1. (IMAGE)

Osaka University

Figure 1.

Caption

<b>Persistent infection and, potentially, cancer development are regulated by <i>Helicobacter pylori</i> (<i>H. pylori</i>) small RNA HPnc4160: </b><i>H. pylori</i>'s small RNA HPnc4160 suppresses the expression of messenger RNAs of pathogenic factors. When <i>H. pylori</i> infects the gastric mucosa, a mutation is introduced into a continuous thymidine (T) sequence (T-repeat) located upstream of the gene encoding HPnc4160. Because the amount of HPnc4160 subsequently decreases, the number of pathogenic factors increase and <i>H. pylori</i> can easily infect the gastric mucosa for a long period of time.

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Osaka University

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