NDF Activates Genes (IMAGE) University of California - San Diego Caption Nucleosome destabilizing factor, or NDF, activates genes by destabilizing nucleosomes, clearing the way for genes to activate. Credit Kadonaga Lab, UC San Diego Usage Restrictions Must be used in conjunction with Genes & Development paper on nucleosome destabilizing factor. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.