H1 Histone Embryoid Body Impaired Differentiation (IMAGE)

Georgia Institute of Technology

H1 Histone Embryoid Body Impaired Differentiation

Caption

This image shows hematoxylin and eosin staining of sections of wild-type (top row) and H1 triple-knockout (bottom row) embryoid bodies. After 14 days in rotary suspension culture, the wild-type embryoid bodies showed more differentiated morphologies with cysts forming (black arrows) and the knockout embryoid bodies failed to form cavities (far right).

Credit

Yuhong Fan

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