Neutrophils (IMAGE)

Cold Spring Harbor Laboratory

Neutrophils

Caption

Two enzymes called NE (green dots) and MMP9 (red dots) stud the scaffold of DNA NETs expelled by neutrophils, or white blood cells. These enzymes sequentially cleave a protein called laminin-111 in lung tissue, inducing a signal that causes nearby dormant cancer cells to reawaken and begin proliferating, the seed of a possible metastatic tumor.

Credit

Egeblad lab, Cold Spring Harbor Laboratory

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