Brain organoids (IMAGE)

Johns Hopkins Medicine

Brain organoids

Caption

Photomicrographs demonstrating the impact of T lymphocytes (T cells) associated with the intestinal disease necrotizing enterocolitis (NEC) on myelin -- a fatty material that surrounds and protects nerve cells -- in laboratory-grown mouse brain organoids ("mini-brains") that model the brain of a premature human infant. The left image shows brain organoids from healthy mice with numerous myelin connections between the neurons (bright areas). The right image shows brain organoids exposed to T cells from mice with NEC displaying a distinct reduction in the number of myelin fibers connecting neurons.

Credit

C. Zhou, C. Sodhi and D. J. Hackam, Johns Hopkins Medicine

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.