With and Without KMT2D (IMAGE) University of Pennsylvania School of Medicine Caption When KMT2D was depleted (right) from human skin cells, undifferentiated stem cells could not multiply normally, causing different layers of skin epidermis to become thickened and disorganized. Credit The lab of Brian C. Capell, M.D., Ph.D., Perelman School of Medicine, University Pennsylvania Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.