The Body Clock and Aging (IMAGE) University of California - Irvine Caption 'Caloric restriction works by rejuvenating the biological clock in a most powerful way,' says Paolo Sassone-Corsi, director of UCI's Center for Epigenetics & Metabolism. Credit IRB Barcelona Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.