Flu Immuno-viral Archaelogy (IMAGE)
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This visual abstract reflects how Schmidt et al. used an approach they call "'immuno-viral archaeology'' to probe the history of influenza exposure and antibody response in a single individual. They find that viruses, circulating during a donor's infancy, bind tightly to the germline precursors of six distinct lineages of antibodies targeting the hemagglutinin-receptor-binding site.
Credit
Schmidt et al./<i>Cell Reports</i> 2015
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