Altered Epigenetic Enzyme Expression in Schizophrenia (IMAGE)

Massachusetts General Hospital

Altered Epigenetic Enzyme Expression in Schizophrenia

Caption

Using the PET scan tracer Martinostat, Mass. General Hospital investigators found that expression of HDAC epigenetic enzymes (red) is higher in a brain region (arrows) known to be important for executive functions in healthy control participants (left) than in participants with schizophrenia or schizoaffective disorder (right).

Credit

(Gilbert et. al., <i>Journal of Clinical Investigation</i>)

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