Baffling Chronic Pain Rewires Brain (IMAGE) Northwestern University Caption This 3-D graphic shows the abnormal rewiring of the brain's right hemisphere in patients with complex region pain syndrome. The orange path shows the location of gray matter atrophy and damaged wiring in the anterior cingulate; blue shows damage in the insula; green in the medial prefrontal cortex. Credit A. Vania Apkarian Usage Restrictions none License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.