Asymmetric Spindle (IMAGE)

University of Pennsylvania

Asymmetric Spindle

Caption

Signals from the polarized cell cortex (in green) in mouse oocytes regulate microtubule tyrosination (white) to generate spindle asymmetry in meiosis I. This asymmetry can be exploited by selfish genetic elements to bias their transmission to the egg as a form of meiotic drive.

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University of Pennsylvania

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