Mutated BubR1 Makes a Mess of Chromosome Segregation (IMAGE)

Fox Chase Cancer Center

Mutated BubR1 Makes a Mess of Chromosome Segregation

Caption

Left: Normal metaphase, kinetochores (red dots) attach to chromosomes (not visible), which are then pulled apart by microtubules (green lines). Right: A mutation in BubR1 cause kinetochores to create aberrant attachments to chromosomes, leading to improper segregation.

Credit

Fox Chase Cancer Center

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.