Mutated BubR1 Makes a Mess of Chromosome Segregation (IMAGE)
Caption
Left: Normal metaphase, kinetochores (red dots) attach to chromosomes (not visible), which are then pulled apart by microtubules (green lines). Right: A mutation in BubR1 cause kinetochores to create aberrant attachments to chromosomes, leading to improper segregation.
Credit
Fox Chase Cancer Center
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