Colonic Crypt (IMAGE) University of California - Riverside Caption Balance between the two isoforms, P1 and P2, of nuclear receptor HNF4-alpha in the colonic crypt influences susceptibility to colitis and colon cancer. P1 is seen here in green. P2 is seen in red. Credit Poonamjot Deol, Sladek lab, UC Riverside. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.